Differential metabolic and hepatic transcriptome responses of two miniature pig breeds to high dietary cholesterol

Z Cai, C Yu, D Fu, Y Pan, J Huang, Y Rong, L Deng… - Life sciences, 2020 - Elsevier
… the high-fat and high-cholesterol (HFC) diet in Wuzhishan (… , HFC diets can lead to both
NAFLD and atherosclerosis. … two pig breeds will affect the development of atherosclerosis. …

[HTML][HTML] Accelerated miniature swine models of advanced atherosclerosis: A review based on morphology

D Wang, X Xu, M Zhao, X Wang - Cardiovascular Pathology, 2020 - Elsevier
High-cholesterol/high-fat (HCHF) feeding is considered the … 1a, 1b), even for strains like
Ossabaw and Wuzhishan (which … ) Yucatan miniature swine induced by high cholesterol feeding …

Therapeutic Effect of Wuling Powder on Guizhou Mini-pigs of Hyperlipidemia Model

Z Hui, WU Yanjun, YAO Jin, LU Taofeng… - Laboratory Animal and …, 2021 - slarc.org.cn
induced by a high-fat diet in Guizhou mini-pigs. Methods Twelve … Guizhou mini-pigs were
selected, 4 pigs fed a standard diet (… diet in the inbred strain of the wuzhishan miniature pig[J]. …

Establishment of Type 2 Diabetes Mellitus Models Using High-Fat Diet and STZ in Bama Minipigs

Y Zhao, M Niu, J Yunxiao, Y Jifang, X Lei, D Xin… - 2021 - researchsquare.com
… fed with a high-fat diet or high-cholesterol and high-fat diet for 9 … , and optical microscope of
miniature pig retina. Consequently, … Diet in the Inbred Strain of the Wuzhishan Miniature Pig. …

[HTML][HTML] The traditional Chinese medicine formula Fufang-Zhenzhu-Tiaozhi protects myocardia from injury in diabetic minipigs with coronary heart disease

L Song, D Zhang, C Guo, Z Gu, L Wang, YS Yao… - Biomedicine & …, 2021 - Elsevier
… model in Wuzhishan minipigs by using a high-fat/high-sucrose/high-cholesterol diet (HFSCD) …
The results of HE staining demonstrated progressive atherosclerotic lesions of the LAD in …

Identification of novel genes associated with atherosclerosis in Bama miniature pig

D Ding, Y Zhao, Y Jia, M Niu, X Li… - Animal Models and …, 2024 - Wiley Online Library
… , feeding Wuzhishan Miniature pigs and Bama minipigs a high- cholesterol and high- fat
diet (… diet in the inbred strain of the Wuzhishan miniature pig. Anim Biotechnol. 2018;29:110-118. …

[HTML][HTML] Novel biomaterial for artery patch in swine model with high-fat diet

X Lu, L Han, X Guo, M Wang, S Baradarian… - … in Bioengineering and …, 2021 - frontiersin.org
swine PVP (sPVP) patches were implanted in the carotid and femoral arteries of six Yorkshire
pigs that were fed a regular diet … artery of six Yucatan pigs that were fed a high-fat diet and …

[HTML][HTML] Multi-omic analysis in a metabolic syndrome porcine model implicates arachidonic acid metabolism disorder as a risk factor for atherosclerosis

SS Xu, XL Zhang, SS Liu, ST Feng, GM Xiang… - Frontiers in …, 2022 - frontiersin.org
… for pigs (20); the HED group, in which the pigs were fed with a … , we established a Wuzhishan
minipig model that included … In our study, the inbred Wuzhishan minipigs are particularly …

Establishment of type 2 diabetes mellitus models using streptozotocin after 3 months high-fat diet in Bama minipigs

Y Zhao, M Niu, Y Jia, J Yuan, L Xiang, X Dai… - Animal …, 2023 - Taylor & Francis
… fed a high-fat or high-cholesterol/high-fat diet and injected with … et al. induced type 1 diabetes
in Yucatan miniature pigs with … not induce accelerated atherosclerosis during the 9-month …

[HTML][HTML] Application of the transgenic pig model in biomedical research: a review

J Wei, W Zhang, J Li, Y Jin, Z Qiu - Frontiers in Cell and …, 2022 - frontiersin.org
… GGTA1-knockout Yucatan miniature pig model in this study can … One case of transgenic
Wuzhishan mini pigs was produced by … pigs reproduced the human-like atherosclerotic lesions …